CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 25 enrolled
Drug / intervention
Equimatrix® +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03149172
NCT03149172N/ACompleted

Comparison of Post Tooth Extraction Healing Using Different Xenograft Materials

Tufts University·interventional·Posted May 11, 2017·Updated Sep 25, 2020

In Brief

A clinical study evaluating Equimatrix®, Bio-Oss®, and 1 other intervention for Alveolar Bone Loss. Completed, enrolled 25 participants across 1 site.

Detailed Summary

The purpose of this pilot study is to conduct a interventional prospective clinical trial to evaluate the efficacy of three different xenografts for ridge preservation by comparing the quality of newly formed bone using histomorphometric and micro CT analysis.The three xenograft materials under investigation are Bio-Oss® (bovine derived xenograft), Equimatrix® (equine derived xenograft), and Endobon® (bovine derived xenograft). There are no prospective studies comparing the effectiveness of these three materials, Bio-Oss®, Endobon® and Equimatrix®, when placed in extraction sockets. Participants will be recruited from patients in the TUSDM clinics that require extraction of single rooted non-molar tooth and are treatment planned to receive dental implants in the future. Participants will be randomized to receive one of the three xenograft materials after tooth extraction. The percentage of newly formed bone and bone density will be compared between the three materials 4-6 months after ridge preservation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedMay 11, 2017
Enrollment StartOct 20, 2014
Primary CompletionJun 7, 2016
Study CompletionDec 7, 2016
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 9.1 years ago

Interventions

Equimatrix®device

Ridge preservation bone grafting after tooth extraction

Bio-Oss®device

Ridge preservation bone grafting after tooth extraction

Endobon®device

Ridge preservation bone grafting after tooth extraction