CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 2,160 enrolled
Drug / intervention
Couples-based servicesbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03149237
NCT03149237N/ACompleted

Partners-based HIV Treatment for Sero-concordant Couples Attending Antenatal Care

Vanderbilt University Medical Center·interventional·Posted May 11, 2017·Updated Aug 21, 2023

In Brief

A clinical study evaluating Couples-based services for Human Immunodeficiency Virus. Completed, enrolled 2,160 participants across 1 site.

Detailed Summary

The purpose of this R01 proposal is to evaluate the clinical impact, hypothesized mechanisms of behavior change, and cost-effectiveness of a partners-focused integrated elimination of mother-to-child transmission of HIV (EMTCT) package comprised of: 1) antenatal care-based couples HIV testing, ART enrollment, and care for sero-concordant HIV+ expectant couples; (2) Couples-based treatment in the post-partum period; (3) Couple-based education and skills building; and (4) Treatment continuity with the support of expert-patient (peer) supporters from couples who have successfully navigated EMTCT. This innovative approach to scaling up EMTCT services, if proven feasible and effective, will be adopted in President's Emergency Plan for AIDS Relief (PEPFAR) programs to accelerate progress toward EMTCT and helping families with HIV infection live long, healthy lives.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesMozambique

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedMay 11, 2017
Enrollment StartNov 16, 2017
Primary CompletionMar 1, 2023
Study CompletionJul 23, 2023
TodayJul 2, 2026
Enrollment to primary: 5.3 yearsPosted 9.1 years ago

Interventions

Couples-based servicesbehavioral

Couples-based services, including treatment, counseling and peer mentoring in the community.