CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 18 enrolled
Drug / intervention
Tesofensine/Metoprolol +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03149445
NCT03149445Phase 2Completed

A Double-Blind, Randomized, Placebo-Controlled, Multiple-Dose, Multi-Center Safety and Efficacy Study of Co-Administration of Tesofensine/Metoprolol for 12 Weeks in Adult and Adolescent Patients With Prader-Willi Syndrome (PWS), Followed by Two Open Label 12 Weeks Extension Periods for Adolescent Patients

Saniona·interventional·Posted May 11, 2017·Updated Feb 26, 2024

In Brief

A Phase 2 clinical trial evaluating Tesofensine/Metoprolol and Placebos for Confirmed Genetic Diagnosis of Prader-Willi Syndrome. Completed, enrolled 18 participants across 2 sites in 2 countries.

Detailed Summary

Two-centre, double-blind, placebo-controlled, randomized, and multiple-dose clinical study followed by two open label extension periods.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCzechia, Hungary
Collaborators--

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedMay 11, 2017
Enrollment StartMar 30, 2017
Primary CompletionJul 22, 2019
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 9.1 years ago

Interventions

Tesofensine/Metoprololdrug

Study medication will be administered for 91 days.

Placebosdrug

Study medication will be administered for 91 days.