CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 57 enrolled
Drug / intervention
Theraworx +1 moredevice
Likely dose
8 pumps per leg (upper thigh to foot) applied topically each evening for 14 daysAI-extracted
Key inclusion· 1
  • Experience night-time leg cramps and spasms at least three times per week on average
Key exclusion· 3
  • Pregnancy
  • Previously diagnosed non-RLS sleep disorder
  • Schizophrenia or other neurological disorder

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03159260
NCT03159260N/ACompleted

The Effect of Theraworx/[pH]Uel on Night-time Leg Cramps and Spasm Symptoms Including Quality of Life, Depression and Sleep Quality

Sport and Spine Rehab Clinical Research Foundation·interventional·Posted May 18, 2017·Updated Mar 25, 2019

In Brief

A clinical study evaluating Theraworx and Placebo for Leg Cramp, Nocturnal. Completed, enrolled 57 participants across 1 site.

Detailed Summary

The purpose of this study is to determine the effect of Theraworx/\[pH\]uel on the frequency and severity of night-time cramps and spasms symptoms, including quality of life, depression and sleep quality when compared to a placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedMay 18, 2017
Enrollment StartNov 1, 2016
Primary CompletionJun 1, 2017
Study CompletionDec 30, 2017
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 9.1 years ago

Interventions

Theraworxdevice

Subjects will be instructed to apply the topical foam they have been assigned to their entire upper and lower legs and feet using 8 pumps from the product dispenser per leg (upper thigh to foot) before retiring each evening for the next 14 days. If subjects experience leg cramps or spasms after retiring they will be instructed to reapply to 2 pumps of the foam to the affected area in response to each event. Each morning during the 14 days in which subjects apply the foam they will be asked to complete the Compliance and Symptom Log that documents the incidence and severity of night-time cramps and spasms their use of the foam and any other therapies they used to treat their night-time cramps and spasm.

Placeboother

Subjects will be instructed to apply the topical foam they have been assigned to their entire upper and lower legs and feet using 8 pumps from the product dispenser per leg (upper thigh to foot) before retiring each evening for the next 14 days. If subjects experience leg cramps or spasms after retiring they will be instructed to reapply to 2 pumps of the foam to the affected area in response to each event. Each morning during the 14 days in which subjects apply the foam they will be asked to complete the Compliance and Symptom Log that documents the incidence and severity of night-time cramps and spasms their use of the foam and any other therapies they used to treat their night-time cramps and spasm.