At a glance
ClinicalIndex Comparison Record- ✓Peri-appendicular abscess on CT or MRI
- ✓Extruded appendicolith on CT or MRI
- ✓Visible hole in appendiceal wall on CT or MRI
- ✓Free peritoneal air on CT or MRI
- ✕Immunocompromised state
- ✕History of major abdominal operation
- ✕Previous appendicitis
- ✕Major comorbidities that preclude safe operation
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Optimal Care of Complicated Appendicitis
In Brief
A Phase 4 clinical trial evaluating Early Appendectomy, Interval Appendectomy, and 1 other intervention for Appendicitis and 3 related conditions. Completed, enrolled 40 participants across 1 site.
Detailed Summary
When the appendix becomes infected and inflamed, it is called appendicitis. Sometimes, if the infection and inflammation get worse, the appendix can die or burst, leading to a larger infection or even pus pockets around the appendix. This is called complicated, or perforated, appendicitis. Three common treatments for complicated appendicitis are * appendectomy (removal of the appendix) right away * appendectomy several weeks after the diagnosis * treating the appendicitis without performing an appendectomy This study seeks to determine which of these three approaches is most cost-effective in children with complicated appendicitis.
Study Details
Timeline
Interventions
Removal of the appendix within 24 hours of admission
Removal of the appendix after initial antibiotic treatment and at least 6 weeks of recovery.
Zosyn will be administered unless the patient has a penicillin allergy, in which case patients will receive both ciprofloxacin and metronidazole.