CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,329 enrolled
Drug / intervention
Usual Protein/Amino Acid Group +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03160547
NCT03160547N/ACompleted
CompareCT.gov

The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Registry-based Randomized Trial

Clinical Evaluation Research Unit at Kingston General Hospital·interventional·Posted May 19, 2017·Updated Mar 28, 2022

In Brief

A clinical study evaluating Usual Protein/Amino Acid Group and Higher Protein/Amino Acid Group for Critical Illness and Malnutrition. Completed, enrolled 1,329 participants across 86 sites in 16 countries.

Detailed Summary

The investigator will investigate the effects of higher protein/amino acid dosing (≥2.2 g/kg/d) vs usual protein/amino acid dosing (≤1.2 g/kg/d) on clinical outcomes in nutritionally high risk ill patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCritical Illness, Malnutrition
CountriesArgentina, Australia, Brazil, Canada, Greece, Hong Kong, India, Iran, Japan, Malaysia, Mexico, Panama, Puerto Rico, Saudi Arabia, United Kingdom, United States
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedMay 19, 2017
Enrollment StartNov 21, 2017
Primary CompletionDec 3, 2021
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 9.1 years ago

Interventions

Usual Protein/Amino Acid Groupother

Protein targets will be set using pre-ICU dry actual weight. For patients with BMI \>30, ideal body weight based on a BMI of 25 will be used. We will endorse the guidelines for energy targets set forth by ASPEN/SCCM, especially as it pertains to the obese patient.

Higher Protein/Amino Acid Groupother

Protein targets will be set using pre-ICU dry actual weight. For patients with BMI \>30, ideal body weight based on a BMI of 25 will be used. We will endorse the guidelines for energy targets set forth by ASPEN/SCCM, especially as it pertains to the obese patient.