CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 220 enrolled
Drug / intervention
Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), 2.0% abrasive silica +3 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03160703
NCT03160703N/ACompleted
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A Proof of Principal Study to Investigate the Stain Control of Two Stannous Fluoride Dentifrices

GlaxoSmithKline·interventional·Posted May 19, 2017·Updated Jun 4, 2019

In Brief

A clinical study evaluating Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), 2.0% abrasive silica, Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), abrasive silica (3.5%), and 2 other interventions for Extrinsic Dental Stain and Oral Hygiene. Completed, enrolled 220 participants across 1 site.

Detailed Summary

The purpose of this study is to evaluate and compare the stain build up of two stannous fluoride (SnF2) / sodium tripolyphosphate (STP) dentifrices of differing abrasivity levels, with a marketed standard fluoride dentifrice and a marketed SnF2 dentifrice.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsExtrinsic Dental Stain, Oral Hygiene
CountriesCanada
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedMay 19, 2017
Enrollment StartJul 10, 2017
Primary CompletionAug 25, 2017
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 9.1 years ago

Interventions

Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), 2.0% abrasive silicaother

Participants will apply a full brush head of their dentifrice containing 0.454% SnF2 / 5% STP; 2.0% abrasive silica (RDA\~58) and will brush twice daily (morning and evening) for one timed minute (in their usual manner) and expectorate.

Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), abrasive silica (3.5%)other

Participants will apply a full brush head of their dentifrice containing 0.454% SnF2 / 5% STP; 3.5% abrasive silica (RDA\~77) and will brush twice daily (morning and evening) for one timed minute (in their usual manner) and expectorate.

Sodium Monofluorophosphate (1000 ppm fluoride ), RDA~80other

Participants will apply a full brush head of their dentifrice containing 1000 ppm fluoride as SMFP with moderate abrasivity (RDA\~80) and will brush twice daily (morning and evening) for one timed minute (in their usual manner) and expectorate.

Stannous fluoride (SnF2, 0.454%), RDA~120other

Participants will apply a full brush head of their dentifrice containing 0.454% SnF2 with higher abrasivity (RDA\~120) and will brush twice daily (morning and evening) for one timed minute (in their usual manner) and expectorate.