At a glance
ClinicalIndex Comparison Record- ✓Diagnosed with renal or prostatic disease undergoing elective laparoscopic renal surgical procedure or laparoscopic prostatectomy
- ✓ASA class I-III
- ✓Age >18 years
- ✕Known or suspected neuromuscular disorders impairing neuromuscular function
- ✕Allergy to muscle relaxants, anesthetics, or narcotics
- ✕Family or personal history of malignant hyperthermia
- ✕Pregnant, may be pregnant, or currently breast feeding
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Deep Versus Moderate Neuromuscular Block During Sevoflurane Anesthesia on Intraoperative Surgical Conditions in Patients Undergoing Laparoscopic Renal Surgery
In Brief
A Phase 4 clinical trial evaluating Deep neuromuscular block for Surgical Conditions. Completed, enrolled 98 participants across 1 site.
Detailed Summary
A deep neuromuscular block (NMB) is often associated with improved surgical conditions especially in laparoscopic surgery. We previously showed that deep NMB is superior to a moderate NMB under propofol anesthesia. However, this may not apply to sevoflurane anesthesia and sevoflurane by itself produces some degree of muscle relaxation. We therefore plan to investigate the effect of deep NMB on surgical conditions under sevoflurane anesthesia maintenance.
Study Details
Timeline
Interventions
Deep neuromuscular block will be achieved with high dose rocuronium to achieve a depth of 1-2 twitches post tetanic count