CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 600 enrolled
Drug / intervention
oxycodone/APAP +4 moredrug
Likely dose
oxycodone/APAP 5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03173456
NCT03173456Phase 2Completed
CompareCT.gov

Comparing the Efficacy of Five Oral Analgesics for Treatment of Acute Musculoskeletal Extremity Pain in the Emergency Department

Albert Einstein College of Medicine·interventional·Posted Jun 1, 2017·Updated Feb 1, 2022

In Brief

A Phase 2 clinical trial evaluating oxycodone/APAP, hydrocodone/APAP, and 3 other interventions for Musculoskeletal Pain. Completed, enrolled 600 participants across 1 site.

Detailed Summary

This study compares the efficacy of five oral analgesics: 5 mg oxycodone + 325 mg acetaminophen, 5 mg hydrocodone + 300 mg acetaminophen, 30 mg codeine + 300 mg acetaminophen, 400 mg ibuprofen + 1000 mg acetaminophen, and 800 mg ibuprofen + 1000 mg acetaminophen for the treatment of patients with acute musculoskeletal pain who present to the Emergency Department (ED).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMusculoskeletal Pain
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedJun 1, 2017
Enrollment StartNov 28, 2017
Primary CompletionNov 14, 2019
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 9.1 years ago

Interventions

oxycodone/APAPdrug

Oxycodone/acetaminophen 5 mg-325 mg oral tablet

hydrocodone/APAPdrug

Hydrocodone/Acetaminophen 5 Mg-300 Mg oral tablet

codeine/APAPdrug

Codeine/acetaminophen 30 mg-300mg oral tablet

400 ibuprofen/APAPdrug

ibuprofen/acetaminophen 400 mg-1000mg oral tablet

800 ibuprofen/APAPdrug

ibuprofen/acetaminophen 800 mg-1000 mg oral tablet