CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 36 enrolled
Drug / intervention
Lipid Intake +2 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03173677
NCT03173677N/ACompleted
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Monocyte Differentiation and Macrophage Polarization in Circulation in Response to Macronutrient Intake in Healthy Humans: A Randomized Clinical Study

King Saud Bin Abdulaziz University for Health Sciences·interventional·Posted Jun 2, 2017·Updated Jun 2, 2017

In Brief

A clinical study evaluating Lipid Intake, Glucose intake, and 1 other intervention for Atherosclerosis. Completed, enrolled 36 participants.

Detailed Summary

Macrophages can exhibit distinct phenotypes and functions in response to stimuli and can polarize into one of three distinct phenotypes: a pro-inflammatory (M1), an anti-inflammatory pro-tissue (M2) and metabolically-activated (MMe) macrophage phenotypes. Thirty-six healthy volunteers were recruited and randomized into one of three macronutrient intake groups (glucose, lipids, proteins). This study measured the effects of macronutrient intake on the macrophage differentiation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAtherosclerosis
Countries--
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedJun 2, 2017
Enrollment StartFeb 2, 2016
Primary CompletionApr 24, 2016
Study CompletionApr 29, 2016
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 9.1 years ago

Interventions

Lipid Intakedietary

90 grams whipping cream, 31.5 grams fat, 1.7 grams protein, and 2.25 grams carbohydrate

Glucose intakedietary

300 calories of glucose

Protein intakedietary

Isopure unflavored Whey proteins isolate (WPI) powder containing 26 grams per serving of 100% WPI, stripped of fat, carbs, fillers, sugars, and lactose