At a glance
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Project 2: The Impact of Cigarette Nicotine Content, E-cigarette Nicotine Content, and E-cigarette Flavoring on Smoking Behavior
In Brief
A clinical study evaluating NNC Spectrum Cigarette, VLNC Spectrum Cigarette, and 4 other interventions for Smoking. Completed, enrolled 156 participants across 2 sites.
Detailed Summary
Project 2 will evaluate the impact of very low nicotine content cigarettes, e-cigarette nicotine content, and e-cigarette flavoring on cigarettes smoked per day, nicotine exposure, puff topography, discomfort/dysfunction, other health-related behaviors, nicotine/tobacco dependence, biomarkers of tobacco exposure, intention to quit, compensatory smoking, other tobacco use, cardiovascular function, and perceived risk. Project 2 will also evaluate differences between conditions in compliance with product use and the ability to abstain from cigarette smoking when provided a financial incentive for abstinence from combusted tobacco. This is not a treatment program for smoking.
Study Details
Timeline
Interventions
Participants are provided with normal nicotine content Spectrum Cigarette for 13 weeks.
Participants are provided with very low nicotine content Spectrum Cigarette for13 weeks
Participants are provided with moderate nicotine level e-liquid for 13 weeks
Participants are provided with very low or nicotine-free nicotine level e-liquid for 13 weeks
Participants can choose e-liquid flavors from a selection of tobacco flavors
Participants can choose e-liquid flavors from a selection of flavors that includes tobacco and non-tobacco choices