At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Evaluation of the Antibacterial Effect of Nano Silver Fluoride Versus Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique: A Randomized Clinical Trial
In Brief
A Phase 3 clinical trial evaluating Nano silver fluoride solution and Cavity Cleanser for Dental Caries. Completed, enrolled 44 participants across 1 site.
Detailed Summary
* The teeth of the patients that meet inclusion criteria will be anesthetized, isolated with a rubber dam. * Cavity opened using conventional high-speed rotary instruments. * The central cariogenic biomass and the superficial parts of the necrotic dentine will be removed with round burs. * Caries lesion will be completely removed in the enamel/dentin junction. * The excavation procedure will be terminated as soon as the soft and wet dentine was removed and the remaining tissue was leathery but not hard on exploring. * A dentinal sample will then be collected from the base of the cavity using sterile spoon excavator as a baseline for bacteriological assessment. * Then, application of either intervention or control agent, another dentinal sample will be collected using a sterile excavator and transferred into sterile tubes and transferred to the laboratory for microbiological analysis. * Filling of the cavity with resin composite restoration. * All clinical procedures will be carried out at the same visit.
Study Details
Timeline
Interventions
Nano silver fluoride that composed of silver nanoparticles, chitosan and fluoride that combines preventive and antimicrobial properties.
Moistens dentin surface after cavity preparation using a micro brush.