At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 39 enrolled
Drug / intervention
Carboplatin +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Phase II Trial of Vaginal Cuff Brachytherapy Followed by Adjuvant Chemotherapy With Carboplatin and Dose Dense Paclitaxel in Patients With High-Risk Endometrial Cancer
In Brief
A Phase 2 clinical trial evaluating Vaginal Cuff Brachytherapy, Carboplatin, and 1 other intervention for Endometrial Cancer and 2 related conditions. Completed, enrolled 39 participants across 1 site.
Detailed Summary
The purpose of this study is to determine the feasibility of treatment in patients with high risk endometrial cancer treated by vaginal cuff brachytherapy followed by 3 cycles of dose dense paclitaxel and carboplatin chemotherapy.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedJun 2017
Enrollment StartOct 2017
Primary CompletionDec 2019
Study CompletionOct 2021
TodayJul 2026
First PostedJun 16, 2017
Enrollment StartOct 2, 2017
Primary CompletionDec 13, 2019
Study CompletionOct 6, 2021
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 9.0 years ago
Interventions
Vaginal Cuff Brachytherapyradiation
Within 12 weeks of surgery. Either LDR or HDR brachytherapy will be permitted
Carboplatindrug
Carboplatin IV on day 1 of a 21 day cycle for 3 cycles
Paclitaxeldrug
Paclitaxel IV on days 1,8 and 15 of a 21 day cycle for 3 cycles