CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 12 enrolled
Drug / intervention
Bolus dose of Cefazolin +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03190668
NCT03190668Phase 4Completed
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Skeletal Muscle and Adipose Tissue Concentrations of Cefazolin Comparing Two Different Dosing Regimens During Pediatric Posterior Spinal Fusion Surgery

University of Florida·interventional·Posted Jun 19, 2017·Updated Jul 11, 2023

In Brief

A Phase 4 clinical trial evaluating Bolus dose of Cefazolin, Continuous Cefazolin drip, and 2 other interventions for Idiopathic Scoliosis. Completed, enrolled 12 participants across 1 site.

Detailed Summary

The purpose of this research study is to compare the current standard of care for prophylactic Cefazolin administered every 3 hours intravenously with continuous infusion of Cefazolin during pediatric spinal surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIdiopathic Scoliosis
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
201820192020202120222023202420252026
First PostedJun 19, 2017
Enrollment StartMay 29, 2018
Primary CompletionJun 23, 2022
TodayJul 2, 2026
Enrollment to primary: 4.1 yearsPosted 9.0 years ago

Interventions

Bolus dose of Cefazolindrug

Mode of Cefazolin administration will be a intermittent bolus

Continuous Cefazolin dripdrug

Mode of Cefazolin administration will be a continuous drip

Paraspinal muscle microdialysis cathetersdevice

Two dialysis probes will be inserted into a paraspinal muscle

Subcutaneous microdialysis cathetersdevice

Two dialysis probes will be inserted into a paraspinal subcutaneous region