CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 577 enrolled
Drug / intervention
Semaglutide +1 moredrug
Likely dose
Semaglutide 1.0 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03191396
NCT03191396Phase 3Completed

Efficacy and Safety of Semaglutide 1.0 mg Once-weekly Versus Liraglutide 1.2 mg Once-daily as add-on to 1-3 Oral Anti-diabetic Drugs (OADs) in Subjects With Type 2 Diabetes

Novo Nordisk A/S·interventional·Posted Jun 19, 2017·Updated Oct 15, 2019

In Brief

A Phase 3 clinical trial evaluating Semaglutide and Liraglutide for Diabetes and Diabetes Mellitus, Type 2. Completed, enrolled 577 participants across 92 sites in 12 countries.

Detailed Summary

This study is conducted in Europe. The aim of the study is to compare the effect of semaglutide subcutaneous (s.c., under the skin) 1.0 mg once-weekly to liraglutide s.c.1.2 mg once-daily on blood sugar levels after 30 weeks of treatment in people with type 2 diabetes. The study will last approximately 9 months (37 weeks). Each participant will have 7 visits at the clinic and 3 phone calls with the study doctor. At the visits, participants will have a number of tests, for example: general health checks, blood samples, heart and eye checks etc. Participants will also fill in some forms about their health and satisfaction with their diabetes treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBulgaria, Czechia, Finland, France, Germany, Hungary, Italy, Poland, Slovenia, Spain, Sweden, United Kingdom
Collaborators--

Timeline

Phase 3CompletedFinished
201820192020202120222023202420252026
First PostedJun 19, 2017
Enrollment StartJun 27, 2017
Primary CompletionJul 9, 2018
Study CompletionAug 13, 2018
TodayJul 2, 2026
Enrollment to primary: 1.0 yearsPosted 9.0 years ago

Interventions

Semaglutidedrug

Dose gradually increased to 1.0 mg, given s.c. (under the skin), once-weekly for 30 weeks. Participants will remain on their pre-study anti-diabetic drugs (tablets), if any

Liraglutidedrug

Dose gradually increased to 1.2 mg, given s.c. once-daily for 30 weeks. Participants will remain on their pre-study anti-diabetic drugs, if any