CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 79 enrolled
Drug / intervention
Brinzolamide/Brimonidine FC +2 moredrug
Likely dose
Brinzolamide 1% plus Brimonidine 0.2% fixed combination: 1 drop 1 hour before capsulotomyAI-extracted
Key inclusion· 1
  • ✓Patients scheduled for laser posterior capsulotomy due to posterior capsule opacification after uncomplicated phacoemulsification cataract extraction with posterior chamber IOL implantation
Key exclusion· 9
  • ✕Baseline IOP greater than 21 mmHg
  • ✕Glaucomatous eyes or eyes already under treatment with antiglaucoma medications
  • ✕Any intraocular surgery except uncomplicated cataract surgery
  • ✕Previous photorefractive surgery

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03192826
NCT03192826Phase 4Completed
CompareCT.gov

Study of the Efficacy of Brinzolamide 1% Plus Brimonidine 0.2% Versus Brimonidine 0.2% in the Prevention of Intraocular Pressure Rise After Nd-YAG Laser Capsulotomy

University Hospital of Patras·interventional·Posted Jun 20, 2017·Updated Jul 16, 2019

In Brief

A Phase 4 clinical trial evaluating Brinzolamide/Brimonidine FC, Brimonidine 0.2%, and 1 other intervention for Posterior Capsule Opacification and Ocular Hypertension. Completed, enrolled 79 participants across 1 site.

Detailed Summary

To compare the efficacy of a Brinzolamide/Brimonidine fixed combination (FC) with Brimonidine 0.2% in preventing intraocular pressure (IOP) elevations after neodymium: yttrium-aluminum-garnet (Nd:YAG) laser posterior capsulotomy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPosterior Capsule Opacification, Ocular Hypertension
CountriesGreece
Collaborators--

Timeline

Phase 4CompletedFinished
2017201820192020202120222023202420252026
First PostedJun 20, 2017
Enrollment StartJun 20, 2016
Primary CompletionJul 8, 2017
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 9.0 years ago

Interventions

Brinzolamide/Brimonidine FCdrug

1 drop of Brinzolamide/Brimonidine FC 1 hour before capsulotomy

Brimonidine 0.2%drug

1 drop of Brimonidine 0.2% 1 hour before Nd-YAG capsulotomy

Artificial tearsdrug

1 drop of artificial tears 1 hour before Nd-YAG capsulotomy