CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 80 enrolled
Drug / intervention
Spectrum Research Cigarettesbehavioral
Likely dose
Not stated in record
Key inclusion· 5
  • ✓Age 15-20 years
  • ✓Current daily or near-daily cigarette smoking for at least 3 months
  • ✓Lifetime e-cigarette or electronic nicotine device use on at least 2 occasions
  • ✓Confirmed smoking status: breath CO >5 ppm OR (if CO ≤5 ppm) cotinine assay ≥3 on NicAlert Strip
Key exclusion· 11
  • ✕Unwilling to use research cigarettes or ENDS as part of the study
  • ✕Intention to quit smoking within the next 30 days
  • ✕Use of tobacco products (other than ENDS or roll-your-own) >15 days in past 30 days
  • ✕Medical or psychiatric condition that poses significant health risk or interferes with study participation

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03194256
NCT03194256N/ACompleted
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Effects of Very Low Nicotine Content Cigarettes and E-cigarette Characteristics on Smoking in Adolescents

Brown University·interventional·Posted Jun 21, 2017·Updated Dec 18, 2023

In Brief

A clinical study evaluating Spectrum Research Cigarettes for Smoking, Cigarette and Electronic Cigarettes. Completed, enrolled 80 participants across 1 site.

Detailed Summary

This study is designed to examine how the nicotine content of cigarettes and the nicotine concentration and flavors in e-liquids influence responses to and use of these products in adolescent smokers. Participants will complete a total of six sessions (an in-person screening/baseline session and five lab sessions.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSmoking, Cigarette, Electronic Cigarettes
CountriesUnited States
CollaboratorsWake Forest University, University of Minnesota, National Institute on Drug Abuse (NIDA), Food and Drug Administration (FDA)

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJun 21, 2017
Enrollment StartSep 1, 2018
Primary CompletionOct 28, 2022
Study CompletionNov 30, 2022
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 9.0 years ago

Interventions

Spectrum Research Cigarettesbehavioral

Participants will be assigned to either normal nicotine content cigarettes or very low nicotine content cigarettes.