At a glance
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Safer Conception for Women: PrEP Uptake/Adherence to Reduce Periconception HIV Risk for South African Women
In Brief
A Phase 4 clinical trial evaluating PrEP for Safer Conception for HIV Prevention and Conception. Completed, enrolled 330 participants across 1 site.
Detailed Summary
Women who choose to conceive with an infected or unknown serostatus partner in HIV-endemic settings need prevention strategies to reduce periconception HIV acquisition risk. Women at high risk for acquiring HIV during pregnancy need risk reduction strategies to protect themselves and their babies. Evaluating uptake of and adherence to antiretrovirals as pre-exposure prophylaxis in this population is crucial to understanding whether and how this novel prevention strategy should be incorporated into HIV-risk reduction packages for at- risk women planning or with pregnancy.
Study Details
Timeline
Interventions
Evaluation of uptake of and adherence to PrEP and safer conception strategies including: CHCT, ART for the infected partner, and uptake of contraception for those who decide not to conceive by enrolled women, during periconception and pregnancy follow up.