CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 99 enrolled
Drug / intervention
Walking: Intervention arm in diabetics +5 morebehavioral
Likely dose
Walking: 45 minutes at moderate pace 5 days per week for 8 weeks; Lower body heating: 60 minutes at 40-42°CAI-extracted
Key inclusion· 4
  • ✓Type 2 diabetes with BMI 25-50 kg/m²
  • ✓Age 35-65 years for diabetics
  • ✓Sedentary lifestyle (<60 minutes structured exercise per week)
  • ✓Age 18-65 years for healthy volunteers without type 2 diabetes
Key exclusion· 12
  • ✕Cardiovascular disease (MI, heart failure, CAD, stroke)
  • ✕Renal or hepatic disease
  • ✕Active cancer
  • ✕Autoimmune disease

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03203694
NCT03203694N/ACompleted
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Restoring Vasodilator Actions of Insulin in Patients With Type 2 Diabetes

University of Missouri-Columbia·interventional·Posted Jun 29, 2017·Updated Apr 4, 2024

In Brief

A clinical study evaluating Walking: Intervention arm in diabetics, Walking: No intervention in diabetics, and 4 other interventions for Type 2 Diabetes Mellitus and Obesity. Completed, enrolled 99 participants across 1 site.

Detailed Summary

The purpose of the present study is to determine the effects of increased walking and lower body heating on leg vascular function in patients with type 2 diabetes (T2D).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 2 Diabetes Mellitus, Obesity
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJun 29, 2017
Enrollment StartDec 4, 2017
Primary CompletionMar 10, 2022
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 9.0 years ago

Interventions

Walking: Intervention arm in diabeticsbehavioral

The walking program will consist of 45 minutes of walking (at a moderate pace) 5 days per week for 8 weeks.

Walking: No intervention in diabeticsother

Subjects will be instructed to continue their usual lifestyle for 8 weeks.

Walking: Healthy cohort as reference controlsother

Subjects will be studied at one time only.

Lower body heating: Intervention arm in healthy subjectsbehavioral

This intervention consists of 60 minutes of lower body heating (40-42 degree C).

Lower body heating: Intervention arm in diabeticsbehavioral

This intervention consists of 60 minutes of lower body heating (40-42 degree C) 7 days per week for 7 days.

Lower body heating: Healthy cohort as reference controlsother

Subjects will be studied at one time only.