CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 24 enrolled
Drug / intervention
Perflutren Lipid Microsphere Intravenous Suspension [DEFINITY]drug
Likely dose
Perflutren Lipid Microsphere Intravenous Suspension [DEFINITY] 1.3mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03212326
NCT03212326N/ACompleted
CompareCT.gov

Contrast Enhanced Intracardiac Echocardiography (ICE) for Localization of Myocardial Scar During Ablation of Ventricular Tachycardia

Weill Medical College of Cornell University·interventional·Posted Jul 11, 2017·Updated Jun 12, 2019

In Brief

A clinical study evaluating Perflutren Lipid Microsphere Intravenous Suspension [DEFINITY] for Ventricular Tachycardia and Ischemic Cardiomyopathy. Completed, enrolled 24 participants.

Detailed Summary

There is a high correlation between scar areas identified by contrast-enhanced ICE and scar areas identified by conventional electroanatomic mapping. Therefore, the investigators will assess the utility of contrast-enhanced ICE to identify and localize myocardial scar real-time during VT ablation procedures.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsVentricular Tachycardia, Ischemic Cardiomyopathy
Countries--
CollaboratorsBiosense Webster, Inc.

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJul 11, 2017
Enrollment StartMar 1, 2013
Primary CompletionSep 1, 2018
Study CompletionDec 1, 2018
TodayJul 2, 2026
Enrollment to primary: 5.5 yearsPosted 9.0 years ago

Interventions

Perflutren Lipid Microsphere Intravenous Suspension [DEFINITY]drug

Perflutren 1.3mL diluted in 50 mL is infused intravenously, and intracardiac echo imaging is recorded to analyze for areas of possible myocardial scar, which is then compared with areas of abnormal electrical signal via direct catheter mapping which is performed during ablation of ventricular tachycardia.