At a glance
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Effects of the HiBalance-program: Linking Clinical Signs and Symptoms to Changes in the Brain in People With Parkinson´s Disease
In Brief
A clinical study evaluating HiBalance and Speech and communication therapy for Parkinson Disease and 3 related conditions. Completed, enrolled 95 participants across 1 site.
Detailed Summary
This project aims to determine the effects of the HiBalance program on neuroplastic changes in people with mild to moderate Parkinson´s disease. The main hypothesis is that highly challenging exercise will lead to greater gait and balance ability, increased levels of physical activity and an improved health related quality of life. The investigators further hypothesize that neuroplasticity changes will be seen in corresponding areas of the brain, neuropsychological changes on cognitive test measures, and that exercise will inhibit the degeneration of dopaminergic neurons in the brain through the mediation of neurotrophic factors.
Study Details
Timeline
Interventions
Intervention of highly challenging balance training for 10 weeks.
Intervention conducted by speech and language therapist for 10 weeks.