At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Clinical Evaluation of the Efficacy of a Marketed Dentifrice on Plaque and Gingivitis
In Brief
A clinical study evaluating Arm & Hammer Advance White Brilliant Sparkle (Test product) and Crest Cavity Protection Regular Toothpaste (Negative Control) for Plaque and Gingivitis. Completed, enrolled 181 participants across 1 site.
Detailed Summary
Parallel, double blind, randomized, Institutional Review Board (IRB) -approved study involving approximately 160 subjects to complete. Subjects were randomly assigned to either the test product (Arm \& Hammer Advance White Brilliant Sparkle) or the control (Crest Cavity Protection Regular) based on baseline mean whole-mouth plaque and gingival scores and age.Subjects brushed with their assigned dentifrice two times (2X) daily and were evaluated for gingivitis, bleeding and plaque at Baseline and after 4-, 8-, and 12-weeks of product use. Return to pre-study hygiene regimen for 4 weeks and final evaluation at 16 weeks.
Study Details
Timeline
Interventions
20% sodium bicarbonate
Negative control