CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
Sublingual microcirculation assessmentdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03216850
NCT03216850N/ACompleted
CompareCT.gov

Alterations of Glycocalyx in Critical Illness and During Major Surgery and Approaches for Glycocalyx Protection. Effect of Parenteral Nutrition and Plasma Lipidome on GCX

University Hospital Hradec Kralove·observational·Posted Jul 13, 2017·Updated Nov 27, 2019

In Brief

An observational study evaluating Sublingual microcirculation assessment for Endothelial Dysfunction. Completed, enrolled 15 participants across 1 site.

Detailed Summary

Characterisation of the lipidome and parenteral nutrition modulate the endothelial glycocalyx. The aim of the study A is to detect any influence of the lipid emulsion on the endothelial glycocalyx in patients in critical care. The targeted cohort is patients on ICU with an indication for parenteral nutrition including lipid emulsion. 15 patients are planned to be enrolled. Monitored variables: demographic data, type of the population, type of the lipid emulsion, selected variables of the lipid metabolism, sublingual microcirculation (SDF imaging),

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsEndothelial Dysfunction
CountriesCzechia
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJul 13, 2017
Enrollment StartJan 1, 2018
Primary CompletionAug 31, 2018
Study CompletionDec 31, 2018
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 9.0 years ago

Interventions

Sublingual microcirculation assessmentdevice

Non-invasive investigation of the endothelial glycocalyx in the sublingual microcirculation.