CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 256 enrolled
Drug / intervention
Brensocatib 10 mg +2 moredrug
Likely dose
Brensocatib 10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03218917
NCT03218917Phase 2Completed

Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Center Study to Assess the Efficacy, Safety & Tolerability, and PK of INS1007 Administered Once Daily for 24 Weeks in Subjects With Non-CF Bronchiectasis - The Willow Study

Insmed Incorporated·interventional·Posted Jul 17, 2017·Updated Mar 27, 2023

In Brief

A Phase 2 clinical trial evaluating Brensocatib 10 mg, Brensocatib 25 mg, and 1 other intervention for Non-Cystic Fibrosis Bronchiectasis. Completed, enrolled 256 participants across 108 sites in 14 countries.

Detailed Summary

The purpose of the study is to evaluate if INS1007 can reduce pulmonary exacerbations over a 24-week treatment period in participants with non-cystic fibrosis bronchiectasis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Belgium, Bulgaria, Denmark, Germany, Italy, Netherlands, New Zealand, Poland, Singapore, South Korea, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedJul 17, 2017
Enrollment StartOct 31, 2017
Primary CompletionDec 12, 2019
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 9.0 years ago

Interventions

Brensocatib 10 mgdrug

Administered once per day for 24 weeks

Brensocatib 25 mgdrug

Administered once per day for 24 weeks

Placebodrug

Administered once per day for 24 weeks