CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 44 enrolled
Drug / intervention
Pneumoperitoneum pressureprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03219398
NCT03219398N/ACompleted
CompareCT.gov

Comparison Effect Between Lower Pressure and Standard Pressure Pneumoperitoneum on Sign of Acute Systemic Inflammation, Endothelial Injury, and Acute Kidney Injury: A Randomized Clinical Trial in Living Donor Laparoscopic Nephrectomy

Indonesia University·interventional·Posted Jul 17, 2017·Updated Mar 14, 2019

In Brief

A clinical study evaluating Pneumoperitoneum pressure for Healthy. Completed, enrolled 44 participants across 1 site.

Detailed Summary

This study aimed to evaluate the increase of intraabdominal pressure 12- 14 mmHg caused by pneumoperitoneum resulted from carbon dioxide (CO2) insufflation induce glycocalyx endothelial injury that cause kidney tubular injury on live donor patient that undergo laparoscopic nephrectomy surgery, and decreasing the intraabdominal pressure to 8-10 mmHg during surgery is expected to reduce the injury.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesIndonesia
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJul 17, 2017
Enrollment StartAug 1, 2017
Primary CompletionMar 1, 2018
Study CompletionDec 1, 2018
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 9.0 years ago

Interventions

Pneumoperitoneum pressureprocedure

Subjects were set to 8- 10 mmHg pressure during laparoscopic surgery; Subjects were set to 12-14 mmHg pressure during laparoscopic surgery