At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 160 enrolled
Drug / intervention
Metoclopramide +2 moredrug
Likely dose
Metoclopramide 20mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized Placebo Controlled Trial of IV Metoclopramide for Acute Post-traumatic Headache
In Brief
A Phase 3 clinical trial evaluating Metoclopramide, Diphenhydramine, and 1 other intervention for Post-Traumatic Headache. Completed, enrolled 160 participants across 1 site.
Detailed Summary
Nearly 1.5 million patients present to US emergency departments annually following head trauma. Headache is a frequent symptom of victims of head trauma. The purpose of this study is to see if an intravenous medication called metoclopramide can improve the symptoms of patients with acute post-traumatic headache.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPost-Traumatic Headache
CountriesUnited States
Collaborators--
Timeline
Phase 3CompletedFinished
201820192020202120222023202420252026
First PostedJul 2017
Enrollment StartAug 2017
Primary CompletionApr 2020
TodayJul 2026
First PostedJul 18, 2017
Enrollment StartAug 1, 2017
Primary CompletionApr 1, 2020
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 9.0 years ago
Interventions
Metoclopramidedrug
Metoclopramide 20mg
Diphenhydraminedrug
Diphenhydramine 25mg
Normal salinedrug
100ml normal saline