CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 193 enrolled
Drug / intervention
Motivationally Enhanced Compensatory Cognitive Training +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03225482
NCT03225482N/ACompleted

Cognitive Rehabilitation for Older Veterans With Mild Cognitive Impairment

VA Office of Research and Development·interventional·Posted Jul 21, 2017·Updated Aug 11, 2025

In Brief

A clinical study evaluating Motivationally Enhanced Compensatory Cognitive Training and Goal-focused Supportive Contact for Mild Cognitive Impairment. Completed, enrolled 193 participants across 2 sites.

Detailed Summary

The number of older Veterans with Mild Cognitive Impairment (MCI) seeking care within the Veterans Affairs (VA) health care system is increasing and is expected to increase more rapidly as Vietnam era Veterans age. The cognitive effects of MCI and subsequent neurodegenerative disorders can adversely affect a Veteran's ability to function independently and failure to provide appropriate intervention can result in an increased need for healthcare services and VA benefits in the future. The VA currently spends over $19,000 annually per patient to care for Veterans with dementia (Zhu et al., 2009), and delaying the onset of dementia even by one to two years will result in substantial financial savings to the VA and quality of life gains for the Veteran. Since present pharmacological interventions have demonstrated limited efficacy, alternative treatments are needed. Therefore, an evidence-based cognitive training intervention that optimally addresses the needs of older Veterans with MCI is of critical importance to the VA patient care mission.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJul 21, 2017
Enrollment StartJul 11, 2018
Primary CompletionJun 30, 2024
TodayJul 2, 2026
Enrollment to primary: 6.0 yearsPosted 8.9 years ago

Interventions

Motivationally Enhanced Compensatory Cognitive Trainingbehavioral

ME-CCT is a manualized group-based behavioral intervention (8 weeks, 2 hours per week, 20 hours total) designed to improve cognitive and everyday functioning in patients with MCI.

Goal-focused Supportive Contactbehavioral

SC is a group therapy intervention that provides the same frequency and amount of therapist and other group member contact as ME-CCT, but does not provide training in cognitive strategies, lifestyle strategies, or motivational enhancement. The SC intervention focuses on setting and achieving short or long-term goals.