CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 20 enrolled
Drug / intervention
Oxymetazoline +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03228914
NCT03228914Phase 4Completed
CompareCT.gov

Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgery

The University of Texas Health Science Center, Houston·interventional·Posted Jul 25, 2017·Updated Jan 13, 2021

In Brief

A Phase 4 clinical trial evaluating Oxymetazoline and Epinephrine for Endoscopic Sinus Surgery and Nasal Polyps. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the effects of Oxymetazoline and Epinephrine (which are 2 different nasal decongestants both of which are routinely used before sinus surgery) on blood loss and the surgeon's view of the surgical field during sinus surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEndoscopic Sinus Surgery, Nasal Polyps
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
201820192020202120222023202420252026
First PostedJul 25, 2017
Enrollment StartJun 14, 2018
Primary CompletionAug 29, 2018
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 8.9 years ago

Interventions

Oxymetazolinedrug

Pledgets will be soaked in 0.05% oxymetazoline solution Two pledgets with the associated medication will be placed into the nasal cavity; one along the floor of the nose and another directed towards the middle meatus.

Epinephrinedrug

Pledgets will be soaked in 1:1000 epinephrine solution Two pledgets with the associated medication will be placed into the nasal cavity; one along the floor of the nose and another directed towards the middle meatus.