At a glance
ClinicalIndex Comparison RecordN/ACompleted· 1,424 enrolled
Drug / intervention
Blood Transfusionprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
CSP #599 - Transfusion Trigger After Operations in High Cardiac Risk Patients (TOP)
In Brief
A clinical study evaluating Blood Transfusion for Myocardial Infarction and 2 related conditions. Completed, enrolled 1,424 participants across 16 sites.
Detailed Summary
The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb \< 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion strategy (transfusion trigger at Hb \< 7 gm/dl).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--
Timeline
N/ACompletedFinished
201820192020202120222023202420252026
First PostedJul 2017
Enrollment StartFeb 2018
Primary CompletionJun 2023
Study CompletionMar 2024
TodayJul 2026
First PostedJul 26, 2017
Enrollment StartFeb 5, 2018
Primary CompletionJun 2, 2023
Study CompletionMar 2, 2024
TodayJul 2, 2026
Enrollment to primary: 5.3 yearsPosted 8.9 years ago
Interventions
Blood Transfusionprocedure
Blood Transfusion