At a glance
ClinicalIndex Comparison RecordN/ACompleted· 131 enrolled
Drug / intervention
Morphine +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Efficacy and Side Effects of Intrathecal Morphine in Multimodal Analgesia for Unilateral Total Knee Arthroplasty
In Brief
A clinical study evaluating 50 ug IT morphine, 100 ug IT morphine, and 3 other interventions for Primary Osteoarthritis of Knee Nos. Completed, enrolled 131 participants across 1 site.
Detailed Summary
This study evaluates postoperative numerical pain score and systemic opioid requirement within 48 hours for unilateral total knee arthroplasty. Comparing among 3 groups of intrathecal morphine; 0,50, 100 ug with multimodal analgesia.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPrimary Osteoarthritis of Knee Nos
CountriesThailand
Collaborators--
Timeline
N/ACompletedFinished
201820192020202120222023202420252026
First PostedJul 2017
Enrollment StartAug 2017
Primary CompletionFeb 2019
Study CompletionJul 2019
TodayJul 2026
First PostedJul 28, 2017
Enrollment StartAug 1, 2017
Primary CompletionFeb 1, 2019
Study CompletionJul 31, 2019
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 8.9 years ago
Interventions
50 ug IT morphineprocedure
Spinal block with bupivacaine and intrathecal morphine 50 ug
100 ug IT morphineprocedure
Spinal block with bupivacaine and intrathecal morphine 100 ug
No IT morphineprocedure
Spinal block with bupivacaine and intrathecal morphine 0 ug
Morphinedrug
intrathecal morphine
Bupivacainedrug
0.5 isobaric bupivacaine