CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 54 enrolled
Drug / intervention
Er:YAG laser +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03233165
NCT03233165N/ACompleted
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Comparison Between Two Different High Power Ablative Lasers in the Treatment of Oral Leukoplakia

University of Zagreb·interventional·Posted Jul 28, 2017·Updated Jul 28, 2017

In Brief

A clinical study evaluating Er:YAG laser and Er,Cr:YSGG laser for Leukoplakic Lesions. Completed, enrolled 54 participants.

Detailed Summary

Oral leukoplakia is a precancerous lesion with relatively high malignant transformation potential. They are often treated by wide surgical excisions or conservative retinoids therapy. The use of high power ablative lasers has been proposed as an effective way of treating these lesions safely. The aim of this study was to evaluate efficiency Er:YAG and Er,Cr:YSGG laser, in the treatment of oral leukoplakia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLeukoplakic Lesions
Countries--
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedJul 28, 2017
Enrollment StartFeb 20, 2015
Primary CompletionFeb 20, 2017
Study CompletionMar 20, 2017
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 8.9 years ago

Interventions

Er:YAG laserprocedure

Ablation of the lesions Device: Er:YAG laser (LightWalker AT, Fotona, Slovenia, 2013) with a non-contact X-Runner digitally controled hand-piece. Settings for the Er:YAG laser were as follows: pulse mode was Quantum Square Pulse (QSP), pulse energy of 120mJ, frequency of 20Hz and water sprey level was set to10ml per minute.

Er,Cr:YSGG laserprocedure

Ablation of the lesions Device: Er,Cr:YSGG laser(WaterLase iPlus, Biolase LTD, USA) using contact mode. Settings were subsequent: power 50W, frequency 50Hz and concentration ratio of air and water was 2:4.