CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 23 enrolled
Drug / intervention
Accelerated theta-burst stimulation treatmentdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03240692
NCT03240692N/ACompleted
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Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression (SAINT-TRD)

Stanford University·interventional·Posted Aug 7, 2017·Updated Apr 21, 2022

In Brief

A clinical study evaluating Accelerated theta-burst stimulation treatment for Treatment Resistant Depression. Completed, enrolled 23 participants across 1 site.

Detailed Summary

This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for treatment-resistant depression. In this open label study, all participants will receive accelerated theta-burst stimulation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTreatment Resistant Depression
CountriesUnited States
CollaboratorsSchatzberg, Alan, M.D.

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedAug 7, 2017
Enrollment StartMay 1, 2017
Primary CompletionDec 1, 2019
Study CompletionMar 3, 2020
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 8.9 years ago

Interventions

Accelerated theta-burst stimulation treatmentdevice

All participants will receive intermittent theta-burst stimulation (iTBS) to the left dorsal lateral prefrontal cortex (L-DLPFC). The L-DLPFC will be targeted utilizing the Localite neuronavigation system. Stimulation intensity will be standardized at 90% of resting motor threshold (adjusted for cortical depth). Stimulation will be delivered to L-DLPFC using the Magventure Magpro X100 and/or the NextStim TMS system.