CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 53 enrolled
Drug / intervention
Nivolumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03246958
NCT03246958Phase 2Completed

A Phase 2 Study of Nivolumab Plus Ipilimumab in RAI Refractory, Aggressive Thyroid Cancer With Exploratory Cohorts in Medullary and Anaplastic Thyroid Cancer

Dana-Farber Cancer Institute·interventional·Posted Aug 11, 2017·Updated Jun 19, 2025

In Brief

A Phase 2 clinical trial evaluating Nivolumab and Ipilimumab for Thyroid Cancer. Completed, enrolled 53 participants across 1 site.

Detailed Summary

This research study is studying nivolumab, an investigational drug, in combination with ipilimumab, also an investigational drug, as a possible treatment for thyroid cancer. The drugs involved in this study are: * Nivolumab (Opdivo™) * Ipilimumab (Yervoy™)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsThyroid Cancer
CountriesUnited States

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedAug 11, 2017
Enrollment StartOct 3, 2017
Primary CompletionJan 21, 2021
Study CompletionJul 31, 2021
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 8.9 years ago

Interventions

Nivolumabdrug

Ipilimumab are types of immunotherapy Immunotherapy works by encouraging the body's own immune system to attack cancer cells.

Ipilimumabdrug

Nivolumab are types of immunotherapy. Immunotherapy works by encouraging the body's own immune system to attack cancer cells.