CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
Abdominal subcutaneous biopsies and Blood testprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03260452
NCT03260452N/ACompleted
CompareCT.gov

Comparison of Hematopoietic Stem Cell Activity in Adipose Tissue From Type 2 Diabetic Patients and Healthy Volunteers: Proof of Concept Study. White Adipose Tissue and Type 2 Diabetes Onset: WAT2DO

University Hospital, Toulouse·interventional·Posted Aug 24, 2017·Updated Apr 2, 2019

In Brief

A clinical study evaluating Abdominal subcutaneous biopsies and Blood test for Type2 Diabetes. Completed, enrolled 20 participants across 1 site.

Detailed Summary

Based on solid preclinical results in mice and preliminary data in humans, this study aims to provide the proof of concept of the crucial role of the hematopoietic process occurring in human adipose tissue in the initiation of the inflammatory process at the origin of insulin resistance and type 2 diabetes (T2D). The main objective is to compare the number of pro-inflammatory macrophages derived from human adipose tissue hematopoietic stem cells (HSC) according to their origin, type 2 diabetes subjects or healthy volunteers.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType2 Diabetes
CountriesFrance
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedAug 24, 2017
Enrollment StartJun 28, 2018
Primary CompletionJan 24, 2019
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 8.9 years ago

Interventions

Abdominal subcutaneous biopsies and Blood testprocedure

Abdominal subcutaneous biopsies and blood test for each volunteer.