CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 99 enrolled
Drug / intervention
Metoclopramide +1 moredrug
Likely dose
Metoclopramide 10mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03269435
NCT03269435Phase 4Completed
CompareCT.gov

A Randomized Trial of Greater Occipital Nerve Block With Bupivacaine Versus Intravenous Metoclopramide for Acute Migraine

Montefiore Medical Center·interventional·Posted Aug 31, 2017·Updated Sep 22, 2021

In Brief

A Phase 4 clinical trial evaluating Greater occipital nerve block with bupivacaine and Metoclopramide for Migraine. Completed, enrolled 99 participants across 1 site.

Detailed Summary

We are comparing a type of nerve block called greater occipital nerve block versus standard therapy among patients who present to an emergency department for acute migraine. This is a randomized, double-blind, double dummy study. The greater occipital nerve block will be performed bilaterally with bupivacaine 0.5%. Standard therapy is metoclopramide 10mg IV.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMigraine
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
201820192020202120222023202420252026
First PostedAug 31, 2017
Enrollment StartNov 1, 2017
Primary CompletionMar 21, 2020
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 8.8 years ago

Interventions

Greater occipital nerve block with bupivacaineprocedure

This is a type of peripheral nerve block. 3cc of 0.5% bupivacaine will be injected adjacent to the greater occipital nerve block blaterally

Metoclopramidedrug

Metoclopramide 10mg IV will be administered over 15 minutes