CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 10 enrolled
Drug / intervention
Phototherapy (NB-UVB) via the 3 Series PC & SP phototherapy cabinetdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03270241
NCT03270241N/ACompleted
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Early Molecular Changes in Vitiligo After Narrowband Ultraviolet Therapy

Johns Hopkins University·interventional·Posted Sep 1, 2017·Updated Jan 9, 2024

In Brief

A clinical study evaluating Phototherapy (NB-UVB) via the 3 Series PC & SP phototherapy cabinet for Vitiligo and Dermatology/Skin - Other. Completed, enrolled 10 participants across 1 site.

Detailed Summary

Vitiligo is a chronic acquired cutaneous disease of pigmentation that affects patients' quality of life across all degrees of involvement and severity. Phototherapy, such as Narrow band UVB (NB-UVB), is a clinically indicated treatment for skin lesions. NB-UVB treatment has been shown to promote repigmentation and normalize cellular behaviors. The investigators would like to analyze the change in protein expression and histological change in skin from NB-UVB treatment in participants with Vitiligo. The investigators are recruiting participants with Vitiligo on the body, arms, and/or legs.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsVitiligo, Dermatology/Skin - Other
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedSep 1, 2017
Enrollment StartOct 1, 2017
Primary CompletionMar 14, 2023
TodayJul 2, 2026
Enrollment to primary: 5.5 yearsPosted 8.8 years ago

Interventions

Phototherapy (NB-UVB) via the 3 Series PC & SP phototherapy cabinetdevice

This is an investigator-initiated, single-blinded, ascending dose study of NB-UVB treatment for Vitiligo in adults of 3 treatments for one week. It is designed to measure the molecular changes and re-pigmentation in affected and normal skin of participants with Vitiligo and normal skin in healthy participants.