CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 799 enrolled
Drug / intervention
Very Low Nicotine Content Cigarettes +1 moredrug
Likely dose
Very Low Nicotine Content Cigarettes 0.4 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03272685
NCT03272685Phase 3Completed
CompareCT.gov

Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace Part of "Evaluating New Nicotine Standards for Cigarettes"

University of Minnesota·interventional·Posted Sep 5, 2017·Updated Aug 20, 2024

In Brief

A Phase 3 clinical trial evaluating Very Low Nicotine Content Cigarettes and Normal Nicotine Content Cigarettes for Tobacco Smoking and Nicotine Dependence. Completed, enrolled 799 participants across 6 sites.

Detailed Summary

This project will examine the impact of very low nicotine content (VLNC) cigarettes in a complex tobacco and nicotine product marketplace. We will compare the number of cigarettes smoked and cigarette-free days in an experimental marketplace that contains VLNC cigarettes versus normal nicotine content (NNC) cigarettes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTobacco Smoking, Nicotine Dependence
CountriesUnited States
CollaboratorsDuke University, University of California, San Francisco, Wake Forest University, University of Pennsylvania, Brown University

Timeline

Phase 3CompletedFinished
201820192020202120222023202420252026
First PostedSep 5, 2017
Enrollment StartJun 1, 2018
Primary CompletionSep 30, 2022
Study CompletionJan 10, 2023
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 8.8 years ago

Interventions

Very Low Nicotine Content Cigarettesdrug

0.4 mg nicotine/g tobacco; 9 mg tar

Normal Nicotine Content Cigarettesdrug

15.8 mg nicotine/g tobacco; 9 mg tar