CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 32 enrolled
Drug / intervention
Ketamine +1 moredrug
Likely dose
Ketamine 0.2 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03280017
NCT03280017Phase 4Completed
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Low Dose Intraoperative Intravenous Ketamine in Combination With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain: a Randomized Study

Mahidol University·interventional·Posted Sep 12, 2017·Updated Sep 13, 2022

In Brief

A Phase 4 clinical trial evaluating Ketamine and Normal saline for Pain, Acute and 2 related conditions. Completed, enrolled 32 participants across 1 site.

Detailed Summary

Postoperative pain after thoracic surgery is associated with adverse outcomes. The current strategy to prevent postoperative pain is the use of regional anesthesia and analgesic agents. In video-assisted thoracic surgery (VATS), thoracic paravertebral block has become the standard analgesic regimen which results in decreased postoperative pain and opioid consumption. The investigator would like to study the analgesic efficacy of low dose intravenous ketamine infusion during surgery in combination with thoracic paravertebral block on postoperative pain after VATS in a randomized study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Acute, Pain, Chronic, Pain, Neuropathic
CountriesThailand
Collaborators--

Timeline

Phase 4CompletedFinished
201820192020202120222023202420252026
First PostedSep 12, 2017
Enrollment StartSep 25, 2017
Primary CompletionDec 31, 2018
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 8.8 years ago

Interventions

Ketaminedrug

intravenous ketamine 0.2 mg/kg/hr (concentration 1 mg/ml)

Normal salinedrug

normal saline infusion