CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 237 enrolled
Drug / intervention
CHRP-BBother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03282890
NCT03282890N/ACompleted
CompareCT.gov

Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs

University of Connecticut·interventional·Posted Sep 14, 2017·Updated Aug 17, 2025

In Brief

A clinical study evaluating CHRP-BB for Risk Behavior and 3 related conditions. Completed, enrolled 237 participants across 1 site.

Detailed Summary

This study will evaluate the efficacy and cost-effectiveness of CHRP-BB - an integrated bio-behavioral approach that incorporates the use of PrEP - with an evidence-based behavioral approach aimed at enhancing PrEP adherence and HIV risk reduction among high risk PWUD.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRisk Behavior, HIV/AIDS, Medication Adherence, Substance Abuse
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA), APT Foundation, Inc.

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedSep 14, 2017
Enrollment StartNov 20, 2017
Primary CompletionOct 13, 2023
TodayJul 2, 2026
Enrollment to primary: 5.9 yearsPosted 8.8 years ago

Interventions

CHRP-BBother

The CHRP-BB intervention is a theory-based, manual-guided, HIV risk reduction and PrEP adherence intervention. It is an integrated evidence-based intervention that uses a coping skills training approach to primary prevention and is delivered in a small group modality by two trained intervention facilitators using a motivational enhancement therapeutic style to address high risk drug- and sex-related HIV risk behaviors and PrEP adherence. Importantly, the CHRP-BB intervention includes specific behavioral and mHealth strategies designed and tested to accommodate difficulties stemming from moderate to severe neuro-cognitive impairment (NCI).