CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 23 enrolled
Drug / intervention
Exercise Testing and Trainingbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03283163
NCT03283163N/ACompleted

Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD

VA Office of Research and Development·interventional·Posted Sep 14, 2017·Updated Aug 14, 2024

In Brief

A clinical study evaluating Exercise Testing and Training for Chronic Musculoskeletal Pain and 2 related conditions. Completed, enrolled 23 participants across 1 site.

Detailed Summary

The wars in Iraq and Afghanistan are creating a new generation of Veterans, including an increasing number of women Veterans, who present with comorbid PTSD and chronic pain conditions from recent deployment-related physical injuries and exposure to psychological trauma. Health behavior change has become increasingly important in treating these conditions and proactively preventing long-term negative health sequelae, in order to benefit these Veterans directly and reduce the growing challenges to the healthcare system. The proposed CDA-2 program of research will use an innovative translational research approach to study whether a chronic progressive -based exercise program will reduce chronic pain symptoms in patients with varying degrees of PTSD symptom severity and to elucidate and modify potential PTSD-related deficiencies in neurobiological and psychological responses to exercise to optimize the physical and psychological benefits of exercise for these individuals.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 14, 2017
Enrollment StartAug 25, 2014
Primary CompletionApr 1, 2020
Study CompletionAug 31, 2022
TodayJul 2, 2026
Enrollment to primary: 5.6 yearsPosted 8.8 years ago

Interventions

Exercise Testing and Trainingbehavioral

The study group will perform a baseline maximum load exercise test which will inform the individualized exercise prescription for the participant. Based on a progressive methodology, the participant will engage in 12 weeks of exercise of their choice (walking, running, cycling or swimming) with the goal of working towards a maximum heart rate range of 80% between weeks 6 and 12 of the study.