CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 96 enrolled
Drug / intervention
Lasmiditan +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03286218
NCT03286218Phase 1Completed

A Randomized, Subject- and Investigator-Blind, Placebo and Active-Controlled Study to Assess the Abuse Potential of Lasmiditan

Eli Lilly and Company·interventional·Posted Sep 18, 2017·Updated Jan 10, 2020

In Brief

A Phase 1 clinical trial evaluating Lasmiditan, Alprazolam, and 1 other intervention for Recreational Drug Use and Prescription Drug Abuse (Not Dependent). Completed, enrolled 96 participants across 1 site.

Detailed Summary

The purpose of this study is to assess the abuse potential of study drug lasmiditan. Lasmiditan will be compared to a marketed benzodiazepine, alprazolam (positive control), as well as to placebo (dummy substance that looks like lasmiditan or alprazolam without any active drug) to determine the potential for drug abuse. The dosages will be in tablet form and will be taken orally (by mouth). This study will last about 55 days, including screening. Screening will occur within 28 days prior to qualification phase.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
201820192020202120222023202420252026
First PostedSep 18, 2017
Enrollment StartSep 15, 2017
Primary CompletionNov 20, 2017
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 8.8 years ago

Interventions

Lasmiditandrug

Administered orally

Alprazolamdrug

Administered orally

Placebodrug

Administered orally