At a glance
ClinicalIndex Comparison RecordN/ACompleted· 350 enrolled
Drug / intervention
Total mesorectal excision before 56 days (4-8 weeks) +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Timing of Surgery After Neoadjuvant Chemoradiation on Histopathological Results, Complications, Recurrence and Survivals for Locally Advanced Rectal Cancer
In Brief
A clinical study evaluating Total mesorectal excision before 56 days (4-8 weeks) and Total mesorectal excision after 56 days (8-12 weeks) for Neoplasm, Rectum. Completed, enrolled 350 participants.
Detailed Summary
This study aimed to compare the outcomes of early versus late surgical resection in patients who underwent curative total mesorectal excision after neoadjuvant chemoradiation. Half of the participants will undergo surgery before 8 weeks, while the other half will undergo surgery after 8 weeks.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNeoplasm, Rectum
Countries--
Collaborators--
Timeline
N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartJan 2006
Primary CompletionJan 2017
First PostedSep 2017
Study CompletionJan 2022
TodayJul 2026
First PostedSep 19, 2017
Enrollment StartJan 1, 2006
Primary CompletionJan 1, 2017
Study CompletionJan 1, 2022
TodayJul 2, 2026
Enrollment to primary: 11 yearsPosted 8.8 years ago
Interventions
Total mesorectal excision before 56 days (4-8 weeks)procedure
Low anterior resection or abdominoperineal resection
Total mesorectal excision after 56 days (8-12 weeks)procedure
Low anterior resection or abdominoperineal resection