CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 90 enrolled
Drug / intervention
Pure PRP II +1 morecombination
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03289416
NCT03289416Phase 4Completed

Efficacy of Bone Marrow Aspirate Concentrate Compared With Platelet Rich Plasma for the Treatment of Symptomatic Knee Osteoarthritis: A Randomized, Controlled Clinical Trial

Andrews Research & Education Foundation·interventional·Posted Sep 21, 2017·Updated Apr 20, 2025

In Brief

A Phase 4 clinical trial evaluating Pure PRP II and PureBMC for Knee Osteoarthritis. Completed, enrolled 90 participants across 1 site.

Detailed Summary

This study is intended to compare whether bone marrow aspirate concentrate or platelet rich plasma injections is more effective in treating knee osteoarthritis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedSep 21, 2017
Enrollment StartDec 5, 2013
Primary CompletionFeb 1, 2020
TodayJul 2, 2026
Enrollment to primary: 6.2 yearsPosted 8.8 years ago

Interventions

Pure PRP IIcombination

The Pure PRP II system will be used to collect and concentrate blood into platelet rich plasma that will be injected into the knee.

PureBMCcombination

The PureBMC system will be used to collect and concentrate bone marrow aspirate into bone marrow concentrate that will be injected into the knee.