CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 19 enrolled
Drug / intervention
NCPAP as mode for apnea prevention +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03298035
NCT03298035N/ACompleted
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A Comparison of Non-invasive Ventilation Methods Used to Prevent Endotracheal Intubation Due to Apnea in Very Low Birth Weight Infants

The University of Texas Health Science Center, Houston·interventional·Posted Sep 29, 2017·Updated Feb 7, 2020

In Brief

A clinical study evaluating NCPAP as mode for apnea prevention and NIPPV as rescue mode for apnea prevention for Apnea of Prematurity. Completed, enrolled 19 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether nasal intermittent positive pressure ventilation (NIPPV) reduces the need for endotracheal intubation in very low birth weight infants with persistent apnea who fail nasal continuous positive airway pressure (NCPAP).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsApnea of Prematurity
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedSep 29, 2017
Enrollment StartNov 11, 2017
Primary CompletionDec 31, 2018
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 8.8 years ago

Interventions

NCPAP as mode for apnea preventiondevice

With recurrence of apneic events, infants on NCPAP will have changes made in NCPAP settings per the clinical team's discretion in attempt to prevent future apneic events. If apneic events persist despite NCPAP adjustments, clinicians may intubate based on clinical judgment.

NIPPV as rescue mode for apnea preventiondevice

With recurrence of apneic events, infants will be placed on NIPPV with settings and adjustments per the clinical team's discretion. If apneic events persist despite NIPPV placement and setting adjustments, clinicians may intubate based on clinical judgment.