CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 142 enrolled
Drug / intervention
Commercially available cigaretteother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03306173
NCT03306173N/ACompleted

COMET Study 1: Filter Ventilated Cigarette Substitution in the ETM

Virginia Polytechnic Institute and State University·interventional·Posted Oct 10, 2017·Updated Oct 7, 2025

In Brief

A clinical study evaluating Commercially available cigarette for Substance-Related Disorders. Completed, enrolled 142 participants across 1 site.

Detailed Summary

Early attempts by the tobacco industry to develop "safer" cigarettes led to the widespread introduction of ventilation holes in cigarette filters; however, this design feature may instead increase smoking-related harm and make cigarettes more palatable. The overall goal of this project is to model regulatory restrictions banning cigarette filter ventilation and determine their effects on consumption of both cigarettes and a wide range of alternative tobacco products. Testing potential regulatory actions under controlled conditions will facilitate evidence-based policies that have a net benefit to health.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedOct 10, 2017
Enrollment StartAug 8, 2018
Primary CompletionMar 10, 2020
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 8.7 years ago

Interventions

Commercially available cigaretteother

Commercially available cigarette with either \~0% or \~25% filter ventilation. Menthol flavor will be available in both types.