CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Venous to arterial conversion (v-TAC)other
Likely dose
Not stated in record
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Search/NCT03309410
NCT03309410N/ACompleted
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Is Mathematical Arterialized Peripheral Venous Blood Gas Reliable Compared to Arterial Blood Gas? - a Clinical Validation Study

Aalborg University·observational·Posted Oct 13, 2017·Updated Oct 13, 2017

In Brief

An observational study evaluating Venous to arterial conversion (v-TAC) for Matched-Pair Analysis and 2 related conditions. Completed, enrolled 30 participants.

Detailed Summary

Objective: Arterial blood gas (ABG) analysis is essential in the clinical assessment of potential acutely ill patients. Venous to arterial conversion (v-TAC), a mathematical method, has recently been developed to convert peripheral venous blood gas (VBG) values to arterialized VBG (aVBG) values. The aim of this study was to test the reliability of aVBG compared to ABG in an emergency department (ED) setting. Method: Twenty ED patients were included in this study. ABG and three aVBG samples were collected from each patient. The aVBG samples were processed in three different ways for comparison: aVBG1 was held steady and analysed within 5 minutes; aVBG2 was tilted in 5 minutes and analysed within 7 minutes; aVBG3 was held steady and analysed after 15 minutes. All VBG samples were arterialized using the v-TAC method. ABG and aVBG samples were compared using Lin's Concordance Correlation Coefficient (CCC) and Bland-Altman's analysis.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsMatched-Pair Analysis, Blood Gas Analysis, Emergency Service, Hospital
Countries--
CollaboratorsDepartment of Anesthesiology, North Denmark Regional Hospital, Center for Clinical Research, North Denmark Regional Hospital

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedOct 13, 2017
Enrollment StartSep 1, 2015
Primary CompletionJan 30, 2016
Study CompletionOct 1, 2017
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 8.7 years ago

Interventions

Venous to arterial conversion (v-TAC)other

This was an observational study. Paired arterial blood gas and venous blood gas was drawn from each patient and compared. Venous blood gas was converted to arterial blood gas values using v-TAC.