At a glance
ClinicalIndex Comparison RecordN/ACompleted· 299 enrolled
Drug / intervention
L-carnosine +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Nucleophilic Defense Against PM Toxicity
In Brief
A clinical study evaluating L-carnosine and placebo for Air Pollution Toxicity. Completed, enrolled 299 participants across 1 site.
Detailed Summary
Carnosine is a naturally occurring peptide found in high levels in skeletal muscle and the brain and is also available commercially as a dietary supplement. Since carnosine has anti-oxidant properties and air pollution exposure induces a state of oxidative stress, the purpose of this study is to see if those taking carnosine as a dietary supplement are protected from air pollution-induced oxidative stress and adverse cardiovascular outcomes.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAir Pollution Toxicity
CountriesUnited States
Timeline
N/ACompletedFinished
201820192020202120222023202420252026
First PostedOct 2017
Enrollment StartApr 2018
Primary CompletionNov 2022
TodayJul 2026
First PostedOct 19, 2017
Enrollment StartApr 1, 2018
Primary CompletionNov 1, 2022
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 8.7 years ago
Interventions
L-carnosinedietary
a naturally occurring di-peptide
placeboother
an identically appearing supplement