CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 163 enrolled
Drug / intervention
SPIRIT Interventionbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03315962
NCT03315962N/ACompleted
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Simplified Isoniazid Preventive Therapy (SPIRIT) Strategy to Reduce TB Burden

University of California, San Francisco·interventional·Posted Oct 20, 2017·Updated Jun 18, 2025

In Brief

A clinical study evaluating SPIRIT Intervention for Tuberculosis and HIV/AIDS. Completed, enrolled 163 participants across 1 site.

Detailed Summary

The overall objective of this study is to determine if a multi-component implementation intervention (SPIRIT) and additional leadership and management training that targets District Health Officers (DHOs) can increase IPT initiation among HIV-infected persons, as compared to country standard practices, in a cluster randomized trial in Uganda.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTuberculosis, HIV/AIDS
CountriesUganda
CollaboratorsMakerere University, National Institute of Allergy and Infectious Diseases (NIAID), Cipla Ltd.

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedOct 20, 2017
Enrollment StartNov 15, 2017
Primary CompletionNov 30, 2023
TodayJul 2, 2026
Enrollment to primary: 6.0 yearsPosted 8.7 years ago

Interventions

SPIRIT Interventionbehavioral

The intervention will include implementing a teaching collaborative among group of DHOs and TB Supervisors, enabling text messaging between DHOs and front line providers, and establishing a report collaborative where DHOs will receive feedback on the performance of their district in administering IPT compared to other districts.