CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 29 enrolled
Drug / intervention
Renal Transplantationprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03317925
NCT03317925N/ACompleted
CompareCT.gov

Renal Transplant Injury and the Renin-Angiotensin System in Kids (RETASK)

Wake Forest University Health Sciences·observational·Posted Oct 23, 2017·Updated Nov 8, 2017

In Brief

An observational study evaluating Renal Transplantation for Renal Transplant and 4 related conditions. Completed, enrolled 29 participants across 1 site.

Detailed Summary

In pediatric kidney transplant patients, rejection, medication toxicity and ischemia cause early and chronic renal allograft injury, which reduces graft lifespan and patient survival. Early detection of injury would facilitate prevention and treatment. The gold standard surveillance biopsy has limitations including delayed discovery of injury. No noninvasive test identifies graft injury before it is clinically apparent. This project's goal is to develop a novel early marker of subclinical graft injury to facilitate prompt recognition and treatment.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsRenal Transplant, Renin-Angiotensin System, Rejection Acute Renal, Rejection Chronic Renal, Rejection of Renal Transplant
CountriesUnited States
CollaboratorsStanford University

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedOct 23, 2017
Enrollment StartJul 16, 2014
Primary CompletionJan 20, 2016
Study CompletionApr 26, 2017
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 8.7 years ago

Interventions

Renal Transplantationprocedure

Kidney transplantation and biomarkers that can identify injury after transplant.