At a glance

ClinicalIndex Comparison Record

N/ACompleted· 26 enrolled

Drug / intervention

Multicomponent interventionother

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03329521

NCT03329521N/ACompleted

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Multicomponent Intervention to Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) in Patients With Chronic Kidney Disease: A Pragmatic, Registry-based, Cluster-Randomized Clinical Trial

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's·interventional·Posted Nov 6, 2017·Updated Nov 9, 2023

In Brief

A clinical study evaluating Multicomponent intervention for Kidney Diseases and 2 related conditions. Completed, enrolled 26 participants across 1 site.

Detailed Summary

Compared to dialysis, kidney transplantation is associated with improved survival, better quality of life and substantial cost savings to healthcare systems. Despite these advantages, many individuals with kidney failure will never receive a kidney transplant. A multicomponent intervention (vs. usual care) provided in chronic kidney disease (CKD) programs located in Ontario, Canada was developed to determine if it can enable more patients with no recorded contraindications to kidney transplant to complete more steps towards receiving a kidney transplant. These CKD programs provide care to individuals with CKD (including patients approaching the need for dialysis and patients receiving dialysis). The intervention has four main components: (1) support for local quality improvement teams and administrative needs; (2) tailored education and resources for staff, patients, and living kidney donor candidates; (3) support from kidney transplant recipients and living kidney donors (i.e. Transplant Ambassador Program); and (4) program-level performance reports and oversight by program leaders. The Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) trial will provide high-quality evidence on whether a multicomponent intervention helps patients complete more steps towards receiving a kidney transplant.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsKidney Diseases, Kidney Failure, End Stage Renal Disease

CountriesCanada

CollaboratorsInstitute for Clinical Evaluative Sciences, Canadian Institutes of Health Research (CIHR), Ontario Renal Network (part of Ontario Health), Trillium Gift of Life Network (part of Ontario Health)

Timeline

N/ACompletedFinished

201820192020202120222023202420252026

Enrollment StartNov 2017

First PostedNov 2017

Primary CompletionDec 2021

TodayJul 2026

First PostedNov 6, 2017

Enrollment StartNov 1, 2017

Primary CompletionDec 31, 2021

TodayJul 2, 2026

Enrollment to primary: 4.2 yearsPosted 8.7 years ago

Interventions

Multicomponent interventionother

Patients in 13 of the 26 CKD programs will receive a multicomponent intervention or usual care. The intervention has four main components: (1) support for local quality improvement teams and administrative needs; (2) tailored education and resources for staff, patients, and living kidney donor candidates; (3) support from kidney transplant recipients and living kidney donors; and (4) program-level performance reports and oversight by program leaders.